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MPS III: Bioinformatics
120 Minutes
Massively parallel sequencing (MPS) is an exciting technology that holds promise for enhancing the capabilities of the forensic DNA analyst. However, there are several challenges that confront implementation of an MPS system into the crime laboratory. These include: training and education on fundamentals of the chemistry, functionality and genetic marker systems, validation criteria and study design, policy and data procedure developments related to CODIS operations, and perceived admissibility and privacy issues. This four-part webinar series will address these and other areas of interest, providing foundational information on the two available MPS systems, covering platforms and chemistries, throughput, genetic markers, bioinformatics, validation requirements, applications, and potential admissibility issues.
In this third webinar, Bioinformatics, we will discuss the different software tools available for data processing from raw data to variant identification, as well as specialized tools specifically designed for STR, mtDNA and SNP analysis. Furthermore, we will discuss the potential increased ability for mixture deconvolution and interpretation using data from the MPS platforms. These discussion will clearly identify the potential benefits this promising technology can bring to forensic science.

Speaker

Multiple Presenters
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This event is funded through a Cooperative Agreement (2011-DN-BX-K564) from the National Institute

of Justice (NIJ), Office of Justice Programs (OJP), and U.S. Department of Justice (USDOJ). The views,

policies, and opinions expressed are those of the authors and contributors and do not necessarily reflect

those of the NIJ, OJP, or USDOJ.